葛均波科研成就科研综述葛均波在国际上首次发现心肌桥特异性超声影像学诊断指标“半月现象”和“指尖现象”；主持研制了中国首例可降解涂层新型冠脉支架；作为首位中国国内学者在美国TCT会议上首创“逆行钢丝对吻技术”；成功实施中国国内首例经皮主动脉瓣置入术、经皮二尖瓣修复术及经皮肺动脉成形术 

2022年，葛均波、孙爱军研究团队两项“新发现”在《循环》杂志发表，分别为以“心脏原位巨噬细胞来源的legumain通过促进心肌梗死后凋亡心肌细胞的清除和降解来改善心脏修复“（cardiac resident macrophage-derived legumain improves cardiac repair via promoting clearance and degradation of apoptotic cardiomyocytes after myocardial infarction）；“legumain介导的平滑肌细胞表型转化促进主动脉夹层（legumain is an endogenous modulator of integrin αvβ3 triggering vascular degeneration, dissection, and rupture）”

 他们发现，即使暴露在低水平（低于世界卫生组织定义的空气污染水平）的空气污染物中，也可能在一小时内导致急性冠状动脉综合征发作

 2022年5月，葛均波院士团队完成了3种创新医疗器械国内首例植入，其中有2款瓣膜器械产品都是由中国企业研发的，包括一款三尖瓣介入环缩系统（K-clip）和一款经静脉三尖瓣置换系统（Lux-valve）

 学术论著根据2020年10月中国科学院网站显示，葛均波先后发表SCI收录的通讯、第一作者论文150余篇，主编《Intravascular Ultrasound》等中英文学术著作6部 

1、Ge, J., Sun, A., Paajanen, V., Wang, S., Su, C., Yang, Z., ... & Zou, Y. (2008). Molecular and clinical characterization of a novel SCN5A mutation associated with atrioventricular block and dilated cardiomyopathy. Circulation: Arrhythmia and Electrophysiology, 1(2), 83-92.2、Ge, J., Qian, J., Wang, X., Wang, Q., Yan, W., Yan, Y., ... & Liu, X. (2007). Effectiveness and safety of the sirolimus‐eluting stents coated with bioabsorbable polymer coating in human coronary arteries. Catheterization and Cardiovascular Interventions, 69(2), 198-202.3、Ge, J., Li, Y., Qian, J., Shi, J., Wang, Q., Niu, Y., ... & Zou, Y. (2006). Efficacy of emergent transcatheter transplantation of stem cells for treatment of acute myocardial infarction (TCT-STAMI). Heart, 92(12), 1764-1767.4、Ge, J., Zhao, G., Chen, R., Li, S., Wang, S., Zhang, X., ... & Yang, Y. (2006). Enhanced myocardial cathepsin B expression in patients with dilated cardiomyopathy. European journal of heart failure, 8(3), 284-289.5、Ge, J., Shen, C., Liang, C., Chen, L., Qian, J., & Chen, H. (2006). Elevated matrix metalloproteinase expression after stent implantation is associated with restenosis. International journal of cardiology, 112(1), 85-90.6、Ge, J., Jia, Q., Liang, C., Luo, Y., Huang, D., Sun, A., ... & Chen, H. (2005). Advanced glycosylation end products might promote atherosclerosis through inducing the immune maturation of dendritic cells. Arteriosclerosis, Thrombosis, and Vascular Biology, 25(10), 2157-2163.7、Ge, J., Han, Y., Jiang, H., Sun, B., Chen, J., Zhang, S., & Du, Z. (2005). On behalf of the RACTS (A Randomized Prospective Antiplatelet Trial of Cilostazol Versus Ticlopidine in Patients Undergoing Coronary Stenting) Trial Investigators. RACTS: a prospective randomized antiplatelet trial of cilostazol versus ticlopidine in patients undergoing coronary stenting: long-term clinical and angiographic outcome. J Cardiovasc Pharmacol, 46, 162-6.8、Ge, J., Huang, D., Liang, C., Luo, Y., Jia, Q., & Wang, K. (2004). Upregulation of lectinlike oxidized low-density lipoprotein receptor-1 expression contributes to the vein graft atherosclerosis: modulation by losartan. Atherosclerosis, 177(2), 263-268.9、Ge, J., Baumgart, D., Haude, M., Görge, G., von Birgelen, C., Sack, S., & Erbel, R. (1999). RETRACTED ARTICLE: Role of intravascular ultrasound imaging in identifying vulnerable plaques. Herz, 24(1), 32-41.10、Ge, J., Chirillo, F., Schwedtmann, J., Görge, G., Haude, M., Baumgart, D., ... & Erbel, R. (1999). Screening of ruptured plaques in patients with coronary artery disease by intravascular ultrasound. Heart, 81(6), 621-627.11、Ge, J., Liu, F., Bhate, R., Haude, M., Görge, G., Baumgart, D., & Erbel, R. (1999). Does remodeling occur in the diseased human saphenous vein bypass grafts? An intravascular ultrasound study. The International Journal of Cardiac Imaging, 15(4), 295-300.12、Ge, J., Jeremias, A., Rupp, A., Abels, M., Baumgart, D., Liu, F., & Erbel, R. (1999). New signs characteristic of myocardial bridging demonstrated by intracoronary ultrasound and Doppler. European Heart Journal, 20(23), 1707-1716.13、Erbel, R., & Ge, J. (1995). Novel techniques of coronary artery imaging. Current Opinion in Cardiology, 10(6), 626-633.14、Ge, J., Erbel, R., Görge, G., Haude, M., & Meyer, J. (1995). High wall shear stress proximal to myocardial bridging and atherosclerosis: intracoronary ultrasound and pressure measurements. Heart, 73(5), 462-465.15、Ge, J., Erbel, R., Zamorano, J., Haude, M., Kearney, P., Görge, G., & Meyer, J. (1995). Improvement of coronary morphology and blood flow after stenting. The International Journal of Cardiac Imaging, 11(2), 81-87.16、Ge, J., Liu, F., Kearney, P., Görge, G., Haude, M., & Erbel, R. (1995). Acute coronary artery closure following intracoronary ultrasound examination. Catheterization and cardiovascular diagnosis, 35(3), 232-235.17、Ge, J., Haude, M., Görge, G., Liu, F., & Erbel, R. (1995). Silent healing of spontaneous plaque disruption demonstrated by intracoronary ultrasound. European heart journal, 16(8), 1149-1151.18、Ge, J., Liu, F., Görge, G., Haude, M., Baumgart, D., & Erbel, R. (1995). Angiographically'silent'plaque in the left main coronary artery detected by intravascular ultrasound. Coronary artery disease, 6(10), 805-810.19、Ge, J., Liu, F., Kearney, P., Görge, G., Haude, M., Baumgart, D., ... & Erbel, R. (1995). Intravascular ultrasound approach to the diagnosis of coronary artery aneurysms. American heart journal, 130(4), 765-771.20、Ge, J., Erbel, R., Rupprecht, H. J., Koch, L., Kearney, P., Görge, G., ... & Meyer, J. (1994). Comparison of intravascular ultrasound and angiography in the assessment of myocardial bridging. Circulation, 89(4), 1725-1732.21、Ge, J., Erbel, R., Gerber, T., Görge, G., Koch, L., Haude, M., & Meyer, J. (1994). Intravascular ultrasound imaging of angiographically normal coronary arteries: a prospective study in vivo. Heart, 71(6), 572-578.22、Ge, J., Erbel, R., Zamorano, J., Koch, L., Kearney, P., Görge, G., ... & Meyer, J. (1993). Coronary artery remodeling in atherosclerotic disease: an intravascular ultrasonic study in vivo. Coronary artery disease, 4(11), 981-986.承担项目根据2020年10月中国科学院网站显示，葛均波先后承担“863”计划、国家杰出青年基金及重点项目等国家及省部级科研项目20余项 

项目名称项目来源担任职务药物涂层支架在冠心病应用的研制和开发国家863计划项目项目负责人心脑血管疾病发病和防治的基础研究炎症感染因素在心脑血管疾病中的作用国家重点基础研究发展规划973子项目疑难高危冠心病诊疗优化方案的研究上海市医学发展重点基金研究课题血管树突状细胞与动脉粥样硬化免疫机制的研究上海市科委发展基金科研成果奖励根据2020年10月中国科学院网站显示，葛均波先后以第一完成人获国家科技进步奖、国家技术发明奖等省部级以上科技奖励10余项 

获奖时间项目名称奖励名称2005年血管内超声及多普勒技术在冠状动脉疾病诊治中的研究与应用上海市科学技术进步奖一等奖 2006年血管内超声和多普勒技术在冠状动脉疾病诊治中的应用研究国家科技进步奖二等奖（排名第一） 2011年新型可降解涂层冠脉药物洗脱支架的研制国家技术发明奖二等奖（排名第一） 第七届Essen-Mayo-Mainz大会一等奖第二届国际超声心动图大会优秀论文一等奖

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