陈晓亚科研成就科研综述陈晓亚在植物次生代谢(特别是倍半萜生物合成)、棉纤维发育和植物抗虫新技术等方面取得了一批有一定价值的成果,克隆鉴定了棉酚合成途径的一系列酶和调控因子,解析了青蒿素等倍半萜成分合成调控机制;鉴定了棉纤维发育过程中的关键转录调控因子和细胞壁伸展蛋白,为阐明棉纤维和表皮毛发育的分子机制作出了重要贡献;利用棉铃虫防御基因,发展了植物介导的RNA干扰抗虫新技术,推动了相关生物技术的发展
学术论著截至2017年9月,陈晓亚已在中国国内外发表论文百余篇(包括Nature Biotechnology,Plant Cell,Plant Physiology等国际重要刊物),申请或授权专利15项
以下列出代表性论文(*表示通讯作者) :Yu ZX, Wang LJ, Zhao B, Shan CM, Zhang YH, Chen DF, Chen XY*. 2014. Progressive Regulation of Sesquiterpene Biosynthesis in Arabidopsis and Patchouli (Pogostemon cablin) by the miR156-Targeted SPL Transcription Factors. Mol. Plant 8(1): 98-110.Shan CM, Shangguan XX, Zhao B, Zhang XF, Chao LM, Yang CQ, Wang LJ, Zhu HY, Zeng YD, Guo WZ, Zhou BL, Hu GJ, Guan XY, Chen JZ, Wendel JF, Zhang TZ, Chen XY*. 2014. Control of cotton fibre elongation by a homeodomain transcription factor GhHOX3. Nat. Commun. 5:5519 (2014).Mao YB, Xue XY, Tao XY, Yang CQ, Wang LJ, Chen XY*. 2013. Cysteine protease enhances plant-mediated bollworm RNA interference. Plant Mol Biol. 83(1-2): 119-29.Li JX, Fang X, Zhao Q, Ruan JX, Yang CQ, Wang LJ, Miller DJ, Faraldos JA, Allemann RK, Chen XY*, Zhang P*. 2013. Rational engineering plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency. Biochemical Journal 451(3):417-426.Xu B, Gou JY, Li FG, Shangguan XX, Zhao B, Yang CQ, Wang LJ, Yuan S, Liu CJ, Chen XY*. 2013. A Cotton BURP Domain Protein Interacts With α-Expansin and Their Co-Expression Promotes Plant Growth and Fruit Production. Mol. Plant 6 (3): 945-958.Hong GJ, Xue XY, Mao YB, Wang LJ, Chen XY*. 2012. Arabidopsis MYC2 Interacts with DELLA Proteins in Regulating Sesquiterpene Synthase Gene Expression. Plant Cell 24: 2635–2648.Tao XY, Xue XY, Huang YP, Chen XY and Mao YB*. 2012. Gossypol-enhanced P450 gene pool contributes to cotton bollworm tolerance to a pyrethroid insecticide. Molecular Ecology 21, 4371–4385.Yu ZX, Li JX, Yang CQ, Hu WL, Wang LJ, and Chen XY*. 2012. The Jasmonate-Responsive AP2/ERF Transcription Factors AaERF1 and AaERF2 Positively Regulate Artemisinin Biosynthesis in Artemisia annua L. Mol. Plant 5(2): 353-365.Zhang T et al. 2015. Sequencing of allotetraploid cotton (Gossypium hirsutum L. acc. TM-1) provides a resource for fiber improvement. Nature Biotechnology 33,531–537.承担项目截至2017年9月,陈晓亚先后负责承担国家973、863、基金委重点、创新研究群体等科研项目
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