万建民科研成就科研综述万建民长期从事水稻优异基因挖掘和分子育种研究，在中国国内较早提出和初步实践了作物分子设计育种

在水稻籼粳交杂种优势利用基础研究、品质优异基因挖掘、抗病虫新基因挖掘和优质高产多抗粳稻新品种选育等方面取得重要进展

 1993年至2015年12月，万建民带领团队相继发现了9个籼粳交雌配子和8个雄配子不育位点，分别占中国国内外已报道的62.5%和43.75%，并在相应位点发现广亲和基因；聚合不同位点的广亲和基因，创制广亲和不育系和恢复系，组配的籼粳交新组合结实率稳定在85%以上，有效解决了籼粳交配子体败育难题

 万建民还指导团队利用分子标记和辅助选择的方法，通过两种技术路线，聚合S5-n、S7-n、S17-n等不同位点的广亲和基因和光钝感基因Dth8，创制广适强优恢复系W107，由其组配的协优107于2006年在云南永胜县创1287公斤的世界水稻亩产最高纪录

 万建民带领团队摸索出了条纹叶枯病抗性鉴定方法，建立了规模化抗病鉴定技术体系，对10977份种质资源进行了抗性鉴定，筛选出高抗种质212份；并从高抗种质中挖掘抗条纹叶枯病基因QTL 24个，占中国国内外已报道的71%；精细定位主效抗病基因Stv-bi；创建抗条纹叶枯病高产优质水稻分子标记聚合育种技术体系，创制抗条纹叶枯病优质新种质16份

选育出适应不同生态区的早中晚熟系列抗条纹叶枯病高产优质新品种10个，并得到大面积的推广应用；该成果在短时间内，解决了南方粳稻区受条纹叶枯病流行危害的难题，促进了水稻生产的发展

 此外，万建民带领团队通过筛选高抗材料，定位了12个抗褐飞虱基因/QTL；精细定位了广谱高抗基因Bph27，克隆的广谱高抗基因Bph3为编码三个植物凝集素类受体激酶的基因簇，对褐飞虱的抗性具有累加作用，该研究成果2015年发表在Nature Biotech.，同期评论文章给予了高度评价；此外，他们还将Bph3和Bph27导入籼稻品种9311和粳稻品种宁粳3号，创制出优质抗虫新品系，并转让应用于水稻育种

 科技成果奖励据2020年6月中国农业科学院官网显示，万建民先后获国家科技进步一等奖1项、国家技术发明二等奖1项

 项目级别获奖人员或排名“抗条纹叶枯病高产优质粳稻新品种选育及应用”2010年度国家科技进步一等奖万建民，王才林，刘超，李爱宏，姚立生，袁彩勇，徐大勇，盛生兰，钮中一，江玲，周春和，邓建平，何金龙，陈亮明，滕友仁 “抗条纹叶枯病高产优质粳稻新品种选育及应用”教育部2010年度高校十大科技进展第一完成人“水稻籼粳杂种优势利用相关基因挖掘与新品种培育”2014年度国家技术发明二等奖万建民，赵志刚，江玲，程治军，陈亮明，刘世家 水稻矮化多分蘖基因DWARF 53的图位克隆和功能研究教育部2014年度高校十大科技进展第一完成人阐明独脚金内酯调控水稻分蘖和株型的信号途径”2014年度中国科学十大进展第一完成人参考资料：   承担项目据2020年6月南京农业大学农学院官网显示，万建民先后主持国家863、国家自然科学基金等多项重大课题

 来源项目经费时限973课题粒型决定和休眠调控的遗传机制520万元2014.01-2018.12国家自然科学基金重点项目水稻蛋白品质形成关键基因的功能研究316万元2014.01-2018.12国家自然科学基金重点项目水稻蛋白品质形成关键基因的挖掘利用296万元2019.1.1-2022.12.31农业部种子管理局绿色品种特性鉴定评价专项经费100万元2017.1-2017.12农业部种子管理局物种品种资源保护费水稻优异种质资源搜集鉴定和创新100万元2017.1-2017.12农业部种质资源保护项目物种品种资源保护费29万元2018.1-12江苏省农业科技自主创新资金课题水稻优质高产抗病虫营养高效分子育种关键技术研发200万元2016.1-2017.12江苏省科技厅现代农业-重点项目基于分子标记的水稻育种技术创新及新材料创制200万元2017.7 -2020.6江苏省农业农村厅重大品种选育项目抗稻瘟病优良食味水稻新品种创制50万元/年2018.1-2023.9江苏省财政厅基地专项资金项目南京农业大学土桥水稻育种试验示范基地200万元2017.1-12参考资料： 基因品种&专利成果据2020年6月南京农业大学农学院官网显示，万建民克隆水稻重要新基因36个，培育新品种13个，获新品种权22项、发明专利36项

 会议报告截至2015年12月，万建民主持中国作物学会年会等中国国内会议23次，牵头组织作物分子育种等国际会议11次，应邀做大会学术报告32次

 论文著作据2020年6月南京农业大学农学院官网显示，万建民在Science、Nature、Nature Biotechnology、Nature Comminucation、Developmental Cell、PNAS、Plant Cell等SCI刊物发表论文200余篇，出版专著3部

 1.Xiaowen Yu*, Zhigang Zhao*, Xiaoming Zheng, Jiawu Zhou, Weiyi Kong, Peiran Wang, Wenting Bai, Hai Zheng, Huan Zhang, Jing Li, Jiafan Liu, Qiming Wang, Long Zhang, Kai Liu, Yang Yu, Xiuping Guo, Jiulin Wang, Qibing Lin, Fuqing Wu, Yulong Ren, Shanshan Zhu, Xin Zhang, Zhijun Cheng, Cailin Lei, Shijia Liu, Xi Liu, Yunlu Tian, Ling Jiang, Song Ge, Chuanyin Wu†, Dayun Tao†, Haiyang Wang†, Jianmin Wan. A selfish genetic element confers non-Mendelian inheritance in rice. Science, 2018: 360(6393): 1130-11322.Zhou F, Lin QB, Zhu LH, Ren YL, Zhou KN, Shabek N, Wu FQ, Mao HB, Dong W, Gan L, Ma WW, Gao H, Chen J, Yang C, Wang D, Tan JJ, Zhang X, Guo XP, Wang JL, Jiang L, Liu X, Chen WQ, Chu JF, Yan CY, Ueno K, Ito S, Asami T, Cheng ZJ, Wang J, Lei CL, Zhai HQ, Wu CY, Wang HY, Zheng N, Wan JM. D14-SCFD3-dependent degradation of D53 regulates strigolactone signalling. Nature 2013, 504(7480): 406-4103.Yuqiang Liu*, Han Wu*, Hong Chen, Yanling Liu, Jun He, Haiyan Kang, Zhiguang Sun, Gen Pan, Qi Wang, Jinlong Hu, Feng Zhou, Kunneng Zhou, Xiaoming Zheng, Yulong Ren, Liangming Chen, Yihua Wang, Zhigang Zhao, Qibing Lin, Fuqing Wu, Xin Zhang, Xiuping Guo, Xianian Cheng, Ling Jiang, Chuanyin Wu, Haiyang Wang, Jianmin Wan. A gene cluster encoding lectin receptor kinases confers broad-spectrum and durable insect resistance in rice. Nature Biotechnology. 2015, 33: 301-3074.Qibing Lin, Fuqing Wu, Peike Sheng, Zhe Zhang, Xin Zhang, Xiuping Guo, Jiulin Wang, Zhijun Cheng, Jie Wang, Haiyang Wang, Jianmin Wan. The SnRK2-APC/CTE regulatory module mediates the antagonistic action of gibberellic acid and abscisic pathways. NATURE COMMUNICATIONS | 2015, 6:7981 | DOI: 10.1038/ncomms89815.Qi Wang, Yuqiang Liu, Jun He, Xiaoming Zheng, Jinlong Hu, Yanling Liu, Huimin Dai, Yingxin Zhang,Baoxiang Wang, Weixun Wu, He Gao, Yunhui Zhang, Xiaorong Tao, Huafeng Deng, Dingyang Yuan, Ling Jiang, Xin Zhang, Xiuping Guo, Xianian Cheng, Chuanyin Wu, Haiyang Wang, Longping Yuan, Jianmin Wan. STV11 encodes a sulphotransferase and confers durable resistance to rice stripe virus. NATURE COMMUNICATIONS, 2014, 5:4768, DOI: 10.1038/ ncomms57686.Lin Q, Wang D, Dong H, Gu S, Cheng Z, Gong J, Qin R, Jiang L, Li G, Wang JL, Wu F, Guo X, Zhang X, Lei C, Wang H, Wan J. Rice APC/C-TE controls tillering by mediating the degradation of MONOCULM 1. NATURE COMMUNICATIONS 2012, 3, 20 DOI: 10.1038/ncomms17167.Zhigang Zhao, Yunhui Zhang, Xi Liu, Xin Zhang, Shichang Liu, Xiaowen Yu, Yulong Ren, Xiaomin Zheng, Kunneng Zhou, Ling Jiang, Xiuping Guo, Ying Gai, Chuanyin Wu, Huqu Zhai, Haiyang Wang, Jianmin Wan. A role for a dioxygenase in auxin metabolism and reproductive development in rice. Developmental Cell 2013, 27(1):113-1228.He Gao, Mingna Jin, Xiao-Ming Zheng, Jun Chen, Dingyang Yuan, Yeyun Xin, Maoqing Wang, Dongyi Huang, Zhe Zhang, Kunneng Zhou, Peike Sheng, Jin Ma, Weiwei Ma, Huafeng Deng, Ling Jiang,Shijia Liu, Haiyang Wang, Chuanyin Wu, Longping Yuan, Jianmin Wan.. Days to heading 7, a major quantitative locus determining photoperiod sensitivity and regional adaptation in rice. PNAS,2014, 111(46):16337-163429.Weixun Wu, Xiao-Ming Zheng, Guangwen Lu, Zhengzheng Zhong. He Gao, Liping Chen, Chuanyin Wu, Hong-Jun Wang, Qi Wang, Kunneng Zhou, Jiu-Lin Wang, Fuqing Wu, Xin Zhang, Xiuping Guo, Zhijun Cheng, Cailin Lei, Qibing Lin, Ling Jiang, Haiyang Wang, Song Ge, Jian-Min Wan. The association of functional nucleotide polymorphisms at DTH2 with the northward expansion of rice cultivation in Asia. PNAS, 2013, 110 (8): 2775-278010.YueqinHeng, ChuanyinWu, Yu Long, Sheng Luo, Jin Ma, Jun Chen, Jiafan Liu, HuanZhang, Yulong Ren, Min Wang, Junjie Tan, Shanshan Zhu, Jiulin Wang, Cailin Lei, Xin Zhang, Xiuping Guo, Haiyang Wang, Zhijun Cheng, and Jianmin Wan. OsALMT7 maintains panicle size and grain yield in rice by mediating malate transport. The Plant Cell, 2018. 30: 889–90611.Yihua Wang, Feng Liu, Yulong Ren, Yunlong Wang, Xi Liu, Wuhua Long, Di Wang, Jianping Zhu, Xiaopin Zhu, Ruonan Jing, Mingming Wu, Yuanyuan Hao, Ling Jiang, Chunming Wang, Haiyang Wang, Yiqun Bao, Jianmin Wana, GOLGI TRANSPORT 1B regulates protein export from the endoplasmic reticulum in rice endosperm cells. The Plant Cell, 2016, 28: 2850–2865.12.Shengyang Wu, Yurong Xie, Junjie Zhang Yulong Ren, Xin Zhang, Jiulin Wang, Xiuping Guo, Fuqing Wu, Peike Sheng, Juan Wang, ChuanyinWu, Haiyang Wang, Shanjin Huang, Jianmin Wan. VLN2 regulates plant architecture by affecting microfilament dynamics and polar auxin transport in rice. The Plant Cell, 2015, 27: 2829–284513.Yulong Ren, Yihua Wang, Feng Liu, Kunneng Zhou, Yu Ding, Feng Zhou, Ying Wang, Kai Liu, Lu Gan, Weiwei Ma, Xiaohua Han, Xin Zhang, Xiuping Guo, Fuqing Wu, Zhijun Cheng, Jiulin Wang, Cailin Lei, Qibing Lin, Ling Jiang, Chuanyin Wu, Yiqun Bao, Haiyang Wang, Jianmin Wan. GLUTELIN PRECURSOR ACCUMULATION3 encodes a regulator of post-Golgi vesicular traffic essential for vacuolar protein sorting in rice endosperm. The Plant Cell ,2014, 26(1): 410-42514.Liguo Zhang, Zhijun Cheng, Ruizhen Qin, Yang Qiu, Jiulin Wang, Dan Wang, Xin Zhang, Xiuping Guo, Ling Jiang, Chuanyin Wu, Haiyang Wang, Xiaofeng Cao, Jianmin Wan. Identification and Characterization of an Epi-allele of OsFIE1 Reveals a Regulatory Linkage between two Epigenetic Marks in Rice. The Plant Cell, 2012, 24: 4407-442115.Shirong Zhou,Yang Wang, Wanchang Li, Zhigang Zhao, Yong Wang, Suhai Gu , Qibing Lin , Dan Wang, Ling Jiang, Ning Su, Xin Zhang, Linglong Liu, Zhijun Cheng, Cailin Lei ,Jiulin Wang, Xiuping Guo, Fuqing Wu, Haiyang Wang, Hiroshi Ikehashi, Jianmin Wan. Pollen Semi-Sterility1 Encodes a Kinesin-1 like protein required for male meiosis, anther dehiscence and fertility in rice. The Plant Cell, 2011, 23: 111-12916.Wu CY, Trieu A, Radhakrishnan P, Kwok SF, Harris S, Zhang K, Wang JL, Wan JM, Zhai HQ, Takatsuto S, Matsumoto S, Fujioka S, Feldmann KA, Pennella RI. Brassinosteroids regulate grain filling in rice. The Plant Cell, 2008, 20: 2130–214517.Yang Xu, Jie Yang, Yihua Wang, Jiachang Wang, Yang Yu, Yu Long, Yunlong Wang, Huan Zhang, Yulong Ren, Jun Chen, Ying Wang, Xin Zhang, Xiuping Guo, Fuqing Wu, Shanshan Zhu, Qibing Lin, Ling Jiang, Chuanyin Wu, Haiyang Wang, Jianmin Wan. OsCNGC13 promotes seed-setting rate by facilitating pollen tube growth in stylar tissues. PLoS Genet, 2017, 13(7): e1006906.18.He Gao, Xiao-Ming Zheng, Guilin Fei, Jun Chen, Mingna Jin, Yulong Ren, Weixun Wu, Kunneng Zhou, Peike Sheng, Feng Zhou, Ling Jiang, Jie Wang, Xin Zhang, Xiuping Guo, Jiu-Lin Wang, Zhijun Cheng, Chuanyin Wu, Haiyang Wang, Jian-Min Wan. Ehd4 Encodes a Novel and Oryza-Genus-Specific Regulator of Photoperiodic Flowering in Rice. PLoS Genetics, 2013,9(2): e100328119.Jiafan Liu†, Jun Chen†, Xiaoming Zheng, Fuqing Wu, Qibing Lin, Yueqin Heng, Peng Tian, ZhiJun Cheng, Xiaowen Yu, Kunneng Zhou, Xin Zhang, Xiuping Guo, Jiulin Wang, Haiyang Wang* and Jianmin Wan*. GW5 acts in the brassinosteroid signaling pathway to regulate grain width and weight in rice. NATURE PLANTS, 2017, 3, 17043 | DOI: 10.1038/nplants.2017.4320.Wuhua Long, Yunlong Wang, Susong Zhu, Wen Jing, Yihua Wang, Yulong Ren, Yunlu Tian, Shijia Liu, Xi Liu, Liangming Chen, Di Wang, Mingsheng Zhong, Yuanyan Zhang, Tingting Hu, Jianping Zhu, Yuanyuan Hao, Xiaopin Zhu, Wenwei Zhang, Chunming Wang, Wenhua Zhang, Jianmin Wan. FLOURY SHRUNKEN ENDOSPERM1 connects phospholipid metabolism and amyloplast development in rice. Plant Physiology, 2018, 177: 698-712. 

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